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NIDA

NIDA Genetic Consortium Meeting Abstracts

Revised December 2017

Meeting Abstracts for December 2017

Submitter Title of Abstract Session Number
Hiba Abloushi Genome Wide Association Study of Substance Use Disorder in the United Arab Emirates population A 25
Bianca Acevedo Genetic markers underlying the natural addiction of love C 86
Balasubrahmanyam Addepalli Probing stress-induced effects on RNA and post-transcriptional modifications by LC-MS B 56
Arpana Agrawal Update from the Psychiatric Genetics Consortium 2 5
Marisela Agudelo Single cell imaging flow cytometry as a novel epigenetic tool to detect post-translational modifications and extracellular histone release induced by substance abuse B 57
Schahram Akbarian Nuclear transcriptome and 3D genome mapping in dopaminergic neurons of adult human midbrain 4 12
Ethan Anderson The histone methyltransferase G9a in the nucleus accumbens bidirectionally controls cocaine self-administration, stress-induced reinstatement, and anxiety-like behaviors A 27
Silviu-Alin Bacanu Novel pathway transcriptomics method greatly increases detection of molecular pathways associated with the drugs traits B 58
Jared Bagley Heritable variation in voluntary alcohol drinking in a genetically diverse inbred mouse panel C 87
Lauren Bailey Heritable variation in reward sensitivity and impulsive action and choice in a genetically diverse inbred mouse panel 5 14
Brandon Baker Dissecting the genetic underpinnings of cocaine and methamphetamine consumption in Drosophila melanogaster A 28
Sarah Barry Histone deacetylase 5 nuclear localization mediates epigenetic changes that limit drug reward and suppress relapse to drug-seeking A 29
James Baurley Using artificial intelligence for learning substance use disorder biosignatures C 88
Andrew Bergen Tobacco use disorder treatment biomarkers A 30
Jill Bettinger SWI/SNF chromatin remodeling complexes are required for normal behavioral responses to acute ethanol exposure D 116
Junaid Bhatti Impact of Genetic Polymorphisms on Opioid Misuse: A Scoping Review C 89
Jinbo Bi A Genome-wide Association Analysis with Cocaine Use Disorder Accounting for both Phenotypic Heterogeneity and Gene-Environment Interplay D 117
Jinbo Bi Collaborative Phenotype Inference from Comorbid Substance Use Disorders and Genotypes D 118
Kenneth Blum Genetic Addiction Risk Score (GARS) Predicts Severity, Relapse & Personalized Medicine B 59
Camron Bryant Cyfip1 haploinsufficiency increases compulsive-like behavior and food consumption: Parent-of-origin effects and potential implications for Prader-Willi Syndrome A 31
Camron Bryant Fine mapping of a distal chromosome 1 region influencing opioid addiction traits in a reduced complexity cross D 119
Jason Bubier Detecting genetic variation in morphine LD50 in founder strains of the Collaborative Cross and Diversity Outbred mouse populations 7 20
Shilpa Buch HIV-1 Tat-mediated upregulation of miR-34a activates NF-κB-mediated microglial inflammation via targeting the 3′-UTR of NLRC5 A 32
Nicole Cameron Maternal and Paternal Lineage Contributions to Transgenerational Effects of Prenatal Alcohol Exposure C 90
Dana Carroll Nicotine Metabolite Ratio and Biomarkers of Exposure among American Indian Tobacco Users A 33
Gregory Carter TBD 1 4
Hannah Cates Accumbal E2F3a mediates cocaine behaviors via transcriptome-wide regulation of gene expression and alternative splicing 7 21
Ramesh Chandra Cocaine-induced histone methylation on Egr3 and Nab2 promoters B 60
Sidi Chen Developing direct in vivo genome editing and screening platforms in the mouse brain 5 16
Hao Chen Social behavior and anxiety predicts nicotine self-administration in adolescent outbred rats A 34
Li-Shiun Chen Genetic risk, nicotine dependence, and the clinical benefit of cessation pharmacotherapy D 120
Christine Cheng Massively parallel single-nucleus transcriptomic profiling to identify dysregulated gene regulatory circuitry in opioid addicted human brain 8 23
Elissa Chesler TBD 5 13
Doo-Sup Choi Adolescence Chronic Caffeine Exposure Promotes Diurnal, Biphasic Mood Cycling and Reduces Dendritic Pruning Through DNA Epigenetics in Mice A 35
Pawel Ciborowski Systems Biology Approach to Investigate Epigenetic Regulation of Macrophages Exposed to HIV Infection and Methamphetamine C 91
Shaunna Clark Human alcohol brain methylation and biomarker discovery project A 36
David Cordova The Preliminary Efficacy of a Technology-Based HIV and Drug Abuse Preventive Intervention in a Youth-Centered Community Health Clinic: Opportunities for Incorporating Biomarkers of Exposure and Genetic Susceptibility A 37
Olivia Corradin Identifying pathogenic gene targets of noncoding GWAS risk loci using gene regulatory circuits D 121
Richard Crist Replication of the pharmacogenetic effect of rs678849 on buprenorphine efficacy in African-Americans with opioid use disorder B 61
Matthew Dalva Extracellular Phosphorylation of a Receptor Tyrosine Kinase Controls Synaptic Localization of NMDA Receptors and Regulates Pathological Pain D 122
Imad Damaj Cyfip2 plays an important role in nicotine reward in mice A 38
Mariella De Biasi The CHRNA5 variant rs16969968 alters how dopaminergic function changes during progression toward nicotine addiction and during nicotine withdrawa A 39
Giordano de Guglielmo Identification of genetic variants that contribute to compulsive cocaine and oxycodone intake in rats: Preliminary data and establishment of the cocaine/oxycodone biobanks 6 18
Rajeev Desai Role of N-Methyl-D-Aspartate Receptor (NMDAR) in Co-Morbid Schizophrenia and Substance Abuse D 123
Danielle Dick The Spit for Science project: Characterizing Genetic and Environmental Influences on Patterns of Substance Use in College Students D 124
Elizabeth Do Prenatal Smoke Exposure during Pregnancy and ADHD Symptoms within Offspring: An Examination of Sex Differences and Mediation by DNA Methylation Markers A 40
Stella Dracheva Regulatory signatures in primate neurons at cell type resolution 4 10
Aimee Dudley TBD 1 3
John Dziak The Effect of Varenicline on Ethanol Consumption and Striatal Gene Expression Using Classical Analytical Tools and High-Dimensional Mediation Analysis B 62
Howard Edenberg Transancestral meta-analysis of alcohol dependence identifies novel genetic correlations A 26
Marissa Ehringer Profiling differential expression of miRNA in prefrontal cortices of tobacco smokers vs. non-smokers A 41
Michael Engeln Transcriptional adaptations in the ventral pallidum following cocaine self-administration D 125
Prabagaran Esakky Paternal exposure to cigarette smoke toxicants causes adverse developmental, neurological, and behavioral outcomes in the offspring C 92
Babak Esmail-Azad Opioid Addiction Susceptibility Testing Via Cytochrome P450 Pharmacogenetic And Personalized Brain Region Specific (VTA) Organoid Assays B 63
Earl Ettienne Pharmacogenetics and Opioid Use Disorder C 93
Christie Fowler Nicotine-Mediated Modulation of Choroid Plexus Function and Altered Circulating MicroRNA Expression D 126
Reza Ghanbari Metabolomics Investigation of Opiate Addiction: Golestan Cohort Study C 94
Tom Gould Effects of Nicotine Exposure During Adolescence on Adult Cognition, Dendritic Morphology, and Epigenome C 95
Leonardo  Guercio The Blackfynn Platform for Rapid, Multi-Modal Data Integration, Analysis, and Collaboration to Enable New Approaches to Drug Addiction Research C 96
Peter Hamilton Engineering CRISPR constructs as tools for gene-targeted transcriptional reprogramming in mammalian brain to elucidate the causal pathogenic mechanisms of drug abuse A 42
Joe Harford A Nanocomplex Carrying siRNA Targeting TNFa with Potential to Blunt the Neuroinflammation that Underlies Opioid Tolerance B 64
Elaine Hebda-Bauer Genetics of Novelty Seeking and Propensity for Drug Abuse in Outbred Rats 6 19
Chad Highfill Candidate Genes for Cocaine and Methamphetamine Preference in Drosophila melanogaster A 43
Andrew Jaffe Effects of smoking during pregnancy on the prenatal cortical transcriptome B 65
Eric Johnson NIDA Genetics Consortium Genome-wide Association Study of Opioid Addiction – Wave 1 2 6
Emma  Johnson Large genomewide association study of cannabis dependence: updates from the Substance Use Disorders working group of the Psychiatric Genomics Consortium D 127
Angela Junglen The role of CAMK2A in the comorbidity of PTSD/SUD in individuals seeking detoxification treatment D 128
Caline Karam Genome-wide association analysis of amphetamine sensitivity in Drosophila melanogaster A 44
Marcus Kaul Chronic, low dosage methamphetamine modifies memory performance compromised by exposure to HIV-1 Tat protein A 45
Vivek Kumar CYFIP2 mediated control of cocaine induced neuroadaptations in mice A 46
Daniel Larach Identifying genetic predictors of perioperative opioid use through a prospective cohort of genotyped and phenotyped surgical patients: The Michigan Genomics Initiative B 66
Todd Lencz Large-scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets D 129
Dawei Li Deletions in the SLC25A18 and ZNF490 Genes Associated with Alcohol Dependence–A Genome-wide Copy Number Variation Screen 8 22
Xuan Li Role of dorsal striatal histone deacetylase 5 in incubation of methamphetamine craving C 97
Yutao Liu Serum Exosomes and miRNAs in Male and Female Current, Former and Non-Smokers C 98
Ryan Logan Circadian Rhythms and Opiates: Role of the Circadian Transcription Factor NPAS2 to Regulate Morphine Conditioned Reward C 99
Elizabeth Long The moderating roles of peer group deviance and parental monitoring on polygenic risk for alcohol use across adolescence B 67
Qing Lu A New Artificial Intelligence Tool for Substance Use and Dependence Research 5 15
Trudy MacKay TBD 1 1
Pamela Madden Genetics and Epigenetics: the Addiction Phenotype, and the Adolescent Brain and Cognitive Development Study B 68
Supriya Mahajan Systems Biology Approach to Analysis of the Oral Microbiome in HIV-positive Opiate abusers B 69
Cecilia Marcondes Reactive Oxygen Species induced in innate immune cells by Methamphetamine impact RNA polymerase binding patterns and facilitate the AP-1-mediated transcription of IL1beta and TNFalpha B 70
Christina Markunas Genetically driven gene expression associated with nicotine dependence across ten brain regions reveals novel genes and brain regions 3 9
Luke Matthews Correcting for Genetic and Cultural Nonindependence (Galton’s Problem) when Testing Genetic Associations with Substance Abuse C 100
Ian Maze TBD 9 24
Jacquelyn  Meyers Early Trauma Exposure, Polygenic risk for AUD, and Neural Response Inhibition in Adolescence and Young Adults: Trajectories of Frontal Oscillations during a Go/NoGo Task C 101
Jacquelyn  Meyers Interaction Between Polygenic Risk for Cannabis Use and Environmental Exposures In The Detroit Neighborhood Health Study C 102
Michael Miles Genetic Analysis of Intermittent Access Ethanol Consumption in Diversity Outbred (DO) and Progenitor Mouse Strains C 103
Mahesh Mohan Delta-9-Tetrahydrocannabinol mediated attenuation of gastrointestinal dysfunction in chronic SIV-infected rhesus macaques involves differential modulation of epithelial DNA methylation and T cell activation D 130
Janitza Montalvo-Ortiz Epigenome-wide association study of opioid dependence in European American women C 104
Mike Neale Measurement Non-invariance with Respect to Race and Gender in DSM Criteria for Substance Abuse and Dependence D 131
Elliott Nelson Retrospective accounts of subjective effects of initial opioid use differ between those with opioid use disorder (OUD) and opioid misusers who never progressed to OUD C 105
Sean O'Sullivan Opioid Withdrawal Shifts Amygdalar Transcriptome and is Correlated with Gut Dysbiosis A 47
Chioma Okeoma HIV and substance abuse may influence the evolution of exosomes (exosome speciation): Implication for biosignature D 132
Abe Palmer Genome wide association study of behavioral, physiological and gene expression traits in a multigenerational mouse intercross B 71
Rohan Palmer Multivariate Genetics Architecture of DSM-5 Alcohol Use Disorder B 72
Ying-Xian Pan Aberrant alternative pre-mRNA splicing of the mu opioid receptor gene, OPRM1, in the medial prefrontal cortex of human heroin abusers and heroin self-administering rats D 133
Ying-Xian Pan The role of alternatively spliced mu opioid receptor C-terminal tails in morphine tolerance, physical dependence and reward D 134
Clarissa Parker Measuring negative affective withdrawal in CFW mice: A pilot study A 48
Qian Peng Genome-wide studies uncover a potential burden of uncommon variants and polygenic basis of multiple-substance use disorders in an American Indian population D 135
Francesca Peruzzi A miRNA signature for cognitive deficits and alcohol use disorder in persons living with HIV/AIDS D 136
Andreas Pfenning Cell type and Brain Region-specific Impact of Nicotine Use-associated Genetic Variation 4 11
Robert Philibert The Dose Response and Abstinence induced Reversion Curves for Cigarette and Alcohol Consumption using Clinically Implementable Droplet Digital PCR Assays D 137
Tamara Phillips MA intake and sensitization in mice with a non-functional trace amine-associated receptor 1 A 49
Renato Polimanti Genome-wide association study of opioid dependence in 3,491 cases and 4,163 exposed-controls from the Psychiatric Genomics Consortium A 50
Dina Popova Impact of OPRM1 A118G on synaptic transmission in both human and mouse neurons D 138
Elizabeth Prom-Wormley Genetic and Environmental Contributions to Electronic and Conventional Cigarette Use in Young Adults: A Bivariate Analysis C 106
Sathya Puthanveettil A Long Noncoding RNA Critical for Synapse Function B 73
Jill Rabinowitz The Contributions of Genetic and Contextual Factors to Alcohol and Marijuana Use and Disorders in African-American Young Adults C 107
Upal Roy Role of DJ1 gene in cocaine addiction and HIV-associated cognitive impairment D 139
Laura Saba Introducing the NIDA Core Center of Excellence in Omics, Systems Genetics, and the Addictome 6 17
Sarven Sabunciyan Transcriptome Differences In the Aging Schizophrenia Brain B 74
Wolfgang Sadee Combined genetic influence of the nicotinic receptor gene cluster CHRNA5/A3/B4 on nicotine dependence A 51
Yotam Sagi Chromatin Remodeling Complex in Accumbal Neurons Regulates Reward and Pleasure  B 75
April Shu DNA methylation markers associated with injection drug use status and HIV infection among chronic injection drug users in the ALIVE study C 108
Dani Sisto A Novel Approach to Accounting for Exposure in Genetic Association Studies of Drug Use Disorders – An Update D 140
Christopher Skipwith Building a Predictive Quantitative Genomics Framework for Identifying Endophenotypes in Opioid-Dependent Patients C 109
Matthew Sloan The OPRM1 A118G Polymorphism and Alcohol-Related Phenotypes: Converging Evidence Against Associations with Alcohol Sensitivity and Consumption B 76
Lauren Slosky Self-Administration in Genetically Modified Mice: A Streamlined Platform for the Identification of Addiction Biomarkers, Therapies and Disease Mechanisms B 77
Kristy Soloski Can family cohesion buffer genetic risk for alcohol use trajectories? B 78
Bethany Stangl Dopamine Transporter (Dat1) Gene Variation And Intravenous Alcohol Self-Administration In Non-Dependent Drinkers: Influence Of Sex Differences B 79
Jerry Stitzel Parental nicotine exposure elicits multigenerational nicotine preference and ADHD-like brain, behavioral, and epigenetic anomalies in adolescent mice C 110
Laura Stroud Epigenetic regulation of placenta NR3C1: Mechanism underlying the impact of prenatal marijuana on infant development? D 141
Boris Tabakoff The Construction of a Tool that Predicts the Pathways from the Genome to Phenotype A 52
Yuan-XIing Tao Contribution of DNMT3a to neuropathic pain genesis by downregulating Kcna2 in primary afferent neurons D 142
Lisa Tarantino The Collaborative Cross as a tool for studying the genetics of addiction-related phenotypes B 80
Allison Tegge DNA methylation levels as a biomarker for severity of opioid use C 111
Samikkannu Thangavel Cocaine and HIV- Neuropathogenes: Epigenetic signature of DNA Methylation Role in Brain Energy Metabolism C 112
Thoprgeir Thorgeirsson Results from the Decode GWAS study on addiction 2 7
Vanessa Troiani Clinical and Genetic Risk Factors associated with Opioid Use Disorder in patients with Chronic Pain B 81
Eric Turner Chrna5-expressing neurons in the interpeduncular nucleus mediate aversion primed by prior stimulation or nicotine exposure A 53
Jill Turner Disruption of Hippocampal NRG3-ErbB4 Signaling Ablates Nicotine Withdrawal-Induced Anxiety-like Behaviors A 54
Mudit Tyagi Cocaine-stimulated MSK1 promotes HIV transcription/replication both by augmenting the activity/recruitment of transcription factors and inducing euchromatin structures at HIV LTR B 82
John VanMeter The Role of DRD2 in Adolescent Reward Processing D 143
Jasmin  Vassileva Neurocognitive and personality dimensions of impulsivity as common and specific candidate endophenotypes for opiate and stimulant dependence C 113
Norma Velazquez A Drosophila model for developmental nicotine exposure A 55
Scott Vrieze Genetic associations with alcohol and nicotine use 3 8
Deena Walker Adolescent Social Stress Results in Sex-Specific Transcriptional Reprogramming of The Medial Amygdala, A Critical Region for Sex Differences in Reward B 83
Gemma Wallace Applying advanced statistical modeling to genetic predictors of personality dimensions associated with addiction D 144
Consuelo Walls-Bass Gene Expression Profiling in the Dorsolateral Prefrontal Cortex of Subjects with Completed Suicide and Substance Abuse B 84
Raymond Walters TBD 1 2
Frances Wang Role of Genetically-Influenced 5-HT Functioning in a Bifactor Model of Psychopathology: Moderation by Fathers’ Substance Use Disorder D 145
Craig Werner Trim3 mediates cocaine craving via INO80-dependent transcriptional regulation B 85
Jennifer Wolstenholme Adolescent binge ethanol alters oligodendrocyte maturation and regulation of histone methylation in the PFC C 114
Ke Xu DNA methylation related to HIV-infected smoking associated with mortality in HIV-infected individuals C 115
Abstracts from November 2016 meeting
Submitter Title of Abstract Session Number
Abraham Palmer Genome-wide association study of delay discounting identifies GPM6B and demonstrates co-heritability with smoking Oral Presentation I 1
Arpana Agrawal Psychiatric Genetics Consortium Update Oral Presentation I 2
Thorgeir Thorgeirsson Polygenic risk scores for schizophrenia and bipolar disorder associate with addiction Oral Presentation I 3
Andrew Bergen Smokescreen Translational Analysis Platform: Prediction of Nicotine Metabolism and Smoking Cessation Oral Presentation I 4
Deborah Mash Human Transcriptome Analysis of Cocaine Abuse Identifies Genes Associated with Adult Striatal Neurogenesis Oral Presentation II 1
Amanda Mitchell Longitudinal Assessment of Neuronal 3D Genomes in Mouse Prefrontal Cortex Oral Presentation II 2
Changning Wang EPIS - Epigenetic PET imaging in substance use disorder patients Oral Presentation II 3
Heidi O'Neill Modeling gene x environmental effects in the mouse: the multigenerational phenotypes of the interaction of the rs16969968 SNP with developmental nicotine exposure. Oral Presentation II 4
Venetia Zachariou A unique role of RGSz1 in behavioral responses to pain killers Poster Session I 1
Yi Zhang Neuron subtype-specific molecular profiling and gene editing in a mouse model of cocaine addiction Poster Session I 2
John Rice Targeted sequencing identifies genetic polymorphisms of flavin-containing monooxygenase genes that contribute to the risk of nicotine dependence in European and African Americans Poster Session I 3
Alan R. Prossin Genetic moderation of human sTNFR1 response to experimental pain: potential homeostatic mechanisms underlying endogenous analgesia. Poster Session I 4
Makoto Taniguchi HDAC5 and NPAS4 regulate cocaine reward-environment associations Poster Session I 5
Patrick J. Muholland Integrative synaptomics in heavy drinking macaques identifies cross-species proteogenetic targets for treating excessive drug-seeking Poster Session I 6
Scott J. Moeller Genetic Markers Associated with Brain Structural Abnormalities in Human Cocaine Addiction Poster Session I 7
Caline Karam Delineating the genetic basis of amphetamine sensitivity using a Drosophila behavioral model Poster Session I 8
David Jentsch Intravenous Cocaine Self-Administration in Inbred Mice: Genetic Correlation with Impulsivity and Genome-Wide Association Results Poster Session I 9
Abraham Palmer Genome-wide association study of behavioral, physiological and gene expression traits in outbred CFW mice. Poster Session I 10
Kirk Wilhelmsen Genome-wide meta-analysis identifies seven novel susceptibility signals for nicotine dependence Poster Session I 11
Laura Saba An Influential Novel Transcript in a Systems Genetic Model of Alcohol Consumption Poster Session I 12
Betsy Ferguson A Genome-Wide Approach to Efficiently Identify Replicable DNA Methylation Regions Associated with Alcohol Use Poster Session I 13
Miri Gitik Choline supplementation in an adolescent nicotine exposure model- a whole genome epigenetic perspective. Poster Session I 14
Arpana Agrawal Genomewide association study identifies a novel locus for cannabis dependence Poster Session I 15
S. ZHONG Alcohol-induced histone H3 phosphorylation mediats RNA Pol III gene transcription Poster Session I 16
Alfredo Ghezzi CBP mediated control of long-term drug neuroadaptation in Drosophila Poster Session I 17
Mahesh Mohan Delta-9-Tetrahydrocannabinol mediated attenuation of intestinal inflammation in chronic SIV-infected rhesus macaques involves differential modulation of anti-microbial defensins, pro-inflammatory gene and microRNA expression amidst high viral loads Poster Session I 18
Danielle Dick The Spit for Science project: Characterizing Genetic and Environmental Influences on Patterns of Substance Use in College Students Poster Session I 19
Diana Fishbein Interactions between DAT1 and OPRM1, subcortical volume and later alcohol use in alcohol naïve youth. Poster Session I 20
Kristine Marceau Cortisol-related Genes and Substance Use Severity at age 16 years Poster Session I 21
Mary Kay Lobo Cell subtype transcriptional regulation of mitochondrial dynamics in cocaine action Poster Session I 22
Yuva Kondaveeti Cocaine Induces changes in the expression of lncRNAs in T cells Poster Session I 23
Marcus Kaul HIV-1/gp120 protein and methamphetamine induce lasting alterations in four major neurotransmission systems of the central nervous system Poster Session I 24
Chioma M. Okeoma Cocaine alters semen exosome cargo composition and anti-HIV activity Poster Session I 25
Andew J. Rennekamp Target-agnostic CNS drug discovery using high-throughput behavioral chemical screening in zebrafish larvae identifies a new role for sigma-1 receptors in the vertebrate brain. Poster Session I 26
Qing Lu A New Method Founds Evidence of Genetic Heterogeneity in Nicotine Dependence Poster Session I 27
Jennifer T. Wolstenholme Adolescent binge ethanol alters histone methylation in the PFC leading to lasting memory deficits and increased ethanol sensitivity Poster Session I 28
Chris Bizon Association and Linkage Analysis of Nicotine Dependence from Whole Genome Sequencing of Family Data Suggest a Novel Role for BBS5 Poster Session I 29
Darius Bost Association of addiction phenotypes to predicted transcript levels Poster Session I 30
Gustavo Turecki Impact of chronic cocaine use on the human striatum methylome Poster Session I 31
Elisa M. Trucco A Developmental Perspective on the Role of Genes on Substance Use Disorder Poster Session II 1
Frederick Wolf SIR2/SIRT1 Disinhibition of Gene Expression by Acute Alcohol Leads to Presynaptic Changes and Behavioral Plasticity Poster Session II 2
Joseph Bloom Nicotine Dependence Associated with Functional Variation in FMO3 Poster Session II 3
Peter Hamilton Engineering zinc-finger protein and CRISPR/Cas9 constructs to model the epigenetic and transcriptional phenomena that underlie cocaine-related behaviors Poster Session II 4
Clarissa Parker Genome-wide mapping of ethanol sensitivity in the Diversity Outbred mouse population Poster Session II 5
Boris Tabakoff The Hybird Rat Diversity Rat Panel for Addiction Research Poster Session II 6
Lindsay Farrer Genome-wide Association Study of Amphetamine Related Stimulant Dependence Poster Session II 7
Brian Smith The genetic and epigenetic architecture of behaviors related to drug seeking and abuse: The honey bee as a new animal model Poster Session II 8
Scott Mackey Genetic risk and nicotine exposure interact on the structure and function of the ventromedial prefrontal cortex in adolescents Poster Session II 9
Travis T. Mallard Genome-wide polygenic scores for schizophrenia are associated with substance use during emerging adulthood Poster Session II 10
Lisa Goldberg Identification of a major QTL influencing oxycodone behavioral sensitivity and dependence in C57BL/6 substrains Poster Session II 11
David Brazel Interim results from the GSCAN exome chip project Poster Session II 12
Robert Philibert Quantitative DNA Methylation Analyses Using Digital Droplet PCR Sensitively Detects Surreptitious Smoking in Adolescents. Poster Session II 13
Phillip K. Liu Epigenetics of Drug Sensitization: MicroRNA and HDAC5 expression in Amphetamine-induced Neural Remodeling Poster Session II 14
Gal Yadid Time Window for DNA methylation in Incubation of Cocaine Craving Poster Session II 15
Fereshteh S. Nugent Epigenetic reversal of maternal deprivation-induced dopamine cell hyperexcitability and synaptic mislocalization of AKAP150 within the VTA Poster Session II 16
Pam Madden Genetics, the Addiction Phenotype, and the Adolescent Brain and Cognitive Development Study Poster Session II 17
Ana Ventuneac Integrated (iCare) at Mt. Sinai Poster Session II 18
Michael Stallings Etiological Overlap Between Impaired Sex and Risky Sexual Behavior Poster Session II 19
Kyung-An Han Genetic and social factors critical for inhibitory control Poster Session II 20
Rudra Pratyaydipta Effect of microRNA expression on alcoholism: A study in a panel of recombinant inbred mouse strains Poster Session II 21
Erin Calipari Withdrawal from cocaine self-administration alters the transcriptional profile of cocaine across six brain regions Poster Session II 22
Bradley E. Aouizerat The Women’s Interagency HIV Study (WIHS): A Diverse Cohort Well Suited to Molecular Epidemiology Studies of Substance Abuse Poster Session II 23
Ron Hart Increased nicotine response in iPSC-derived human neurons carrying the CHRNA5 N398 allele Poster Session II 24
Jiang Gui Efficient Survival Multifactor Dimensionality Reduction Method for Detecting Gene-Gene Interaction Poster Session II 25
Anna Dorothy Asimes Pre-conception Maternal and Paternal Binge Alcohol Exposure Lead to Distinct DNA Methylation Patterns in Alcohol-Naive Male Offspring Poster Session II 26
Jinbo Bi Multi-view Singular Value Decomposition for Disease Subtyping and Genetic Associations Poster Session II 27
Ming D. Li A second update on susceptibility genes for nicotine dependence identified by genome-wide linkage, candidate gene association, genome-wide association, and targeted sequencing approaches Poster Session II 28
Nora Bizzozero Neuronal enriched RNA-Binding Protein HuD and microRNA miR-495 oppositely regulate cocaine induced addiction-related gene expression and place preference behavior Poster Session II 29
Ke Xu Identifying the gene co-expression module for tobacco smoking that is regulated by DNA methylation Poster Session II 30
Todd Hulgan Meth and Genetically-Predicted Expression of the Cytoskeletal Protein Spectrin Gene Neurocognitive Function in HIV Poster Session II 31
Caroline Brown Pharmacogenetic Modulation of the Behavioral Effects of Buprenorphine in a Mouse Model of the OPRM1 (A118G) Polymorphism Poster Session III 1
Zhiping Pang Synaptic mechanisms of OPRM1 A118G (MOR N40D) gene variants in human neurons Poster Session III 2
Ethan Carver Gene Regulation and Viability of Cell Cultures Exposed to E-Cigarette Refill Solutions Poster Session III 3
Z Carl Lin EIF3F Genetics of Substance Abuse Poster Session III 4
Dana Hancock Genome-wide Interaction Analysis with Sex Reveals PEX11G as a Novel Gene for Nicotine Dependence Poster Session III 5
Paulo A. Ferreira Control of gene-environment interactions by the Ran-binding protein 2 (Ranbp2) and its stresssensing partners as venues to dissect the genetic basis of addiction behaviors engendered by drug abuse Poster Session III 6
Andon N. Placzek eIF2α-mediated translational control regulates cocaine-and nicotine-induced synaptic potentiation in mouse midbrain dopamine neurons and neuronal responses in human smokers Poster Session III 7
Tamara Phillips Evidence for an epistatic effect of Oprm1 and Taar1 in risk for methamphetamine consumption Poster Session III 8
Roseann Peterson Evidence for shared genetic risk between schizophrenia and smoking behaviors: Findings from the Psychiatric Genomics Consortium. Poster Session III 9
Renato Polimanti Risk alleles identified in a genome-wide gene-by-cannabis dependence interaction analysis of risky sexual behaviors Poster Session III 10
Camron Bryant Cytoplasmic FMR1-interacting protein 2 is a major genetic factor underlying binge eating Poster Session III 11
Shauna Clark Discovering methylation biomarkers of smoking and associated health risks Poster Session III 12
Ashiwel Undieh Psychostimulant-induced Alterations in Epigenetic DNA Methylation of Neural Genes: Toward a Pharmacological Separation of Euphoric and Neuroadaptive Mechanisms? Poster Session III 13
Pradeep Bhide Nicotine-induced DNA methylation in spermatozoa: Consequences for offspring’s behavior and gene expression in the brain Poster Session III 14
Jinying Zhao An Epigenome Wide Association Study on Alcohol Consumption: A Monozygotic Twin Study Poster Session III 15
S.A. Eisenstein Dopamine-related Genetic Profile is Associated with Negative Symptom Severity, Reward Expectancy, and Behavioral Inhibition Poster Session III 16
Su Guo Explore a natural variation of light/dark preference behavior in zebrafish: Genetic or epigenetic? Poster Session III 17
Michael Miles Behavioral genomic and genetic analysis of chronic nicotine and withdrawal in mouse BXD strains. Poster Session III 18
Johana Alvarez Heightened Baseline Anxiety-Like Behavior in Mice with Escalating Cocaine Consumption During Extended Access Cocaine Self-Administration Poster Session III 19
Stephen L. Boehm Short-term selective breeding for adolescent sensitivity to tetrahydrocannabinol- (THC-) induced locomotor sedation in mice. Poster Session III 20
Susan Smith High-Throughput Transcriptome Sequencing to Identify Genetic Modifiers of Sensitivity to Alcohol Poster Session III 21
Christie Fowler Nicotinic Modulation of the Choroid Plexus and Altered Circulating MicroRNA Expression During Chronic Nicotine Self-Administration Poster Session III 22
Shilpa Buch Cocaine-mediated promoter DNA methylation of microRNA-124 promotes microglial activation through TLR4 signaling Poster Session III 23
Gary Siuzdak Cloud-Based Systems Biology Analyses Guided by Metabolomics Poster Session III 24
Jinbo Bi Machine learning to identify highly heritable components of substance use disorders Poster Session III 25
Erika Andrade Neuronal Subtype-Specific Translational Changes Following Extended-Access Cocaine Self-Administration in Mice Poster Session III 26
Sudheesh Pilakka-Kanthikeel Cocaine reactivates latent HIV-1 by down regulating anti-HIV long-non coding RNAs Poster Session III 27
Ming D. Li Characterization of regulatory mechanisms at DNA variant, methylation and RNA levels for 57 tobacco smoking susceptibility genes in human brain Poster Session III 28
Brion Maher Circulating DNA methylation markers associated with injection status and HIV infection among chronic injection drug users in the ALIVE study. Poster Session III 29
Michele T. Juarez Acute exposure of Nicotine during Drosophila puncture injury activates an epidermal wound response Poster Session III 30
Richard C. Crist A polymorphism in the OPRM1 3’ untranslated region is associated with methadone efficacy in treating opioid dependence Poster Session IV 1
Imad Damaj The b3 subunit of the nicotinic acetylcholine receptor (nAChR) is required for nicotine withdrawal but not nicotine reward Poster Session IV 2
Igor Zhulin Establishing the Precise Evolutionary History of a Gene Improves Prediction of Disease-causing Missense Mutations Poster Session IV 3
Li-Shiun Chen Genetic risk can be decreased: Quitting smoking decreases and delays lung cancer for smokers with high and low CHRNA5 risk genotypes - A Meta-analysis Poster Session IV 4
Xiangning Chen Integration of Gene Expression in animal studies with GWAS in human datasets to Identify Risk Genes for Nicotine Dependence Poster Session IV 5
Jared Bagley The effects of prenatal stress on cocaine reward, cocaine locomotion and sensorimotor processing are heritable in the BXD recombinant inbred strain panel Poster Session IV 6
Rohan Palmer Estimation of the Genome-wide Additive Genetic Covariance Across Subjects of European and African Ancestry: An Example Using Alcohol Dependence Poster Session IV 7
Elliot Nelson Meta-analysis of comparisons to non-dependent misusers implicates CD244 involvement in opioid dependence Poster Session IV 8
Kirk Wilhelmsen Whole Genome Sequence Study of Cannabis Dependence: Associations with Regulatory Elements Identified by the Roadmap Epigenomics Project Poster Session IV 9
Eric O. Johnson Multi-ancestry GWAS Identifies Novel Variants Associated with HIV-1 Viral Load Set-point Poster Session IV 10
Laura Stround Epigenetic Regulation of Placental NR3C1: Mechanism Underlying Prenatal Programming of Infant Stress Response by Maternal Smoking During Pregnancy? Poster Session IV 11
Shilpa Buch HIV-1 TAT-mediated epigenetic downregulation of miR-124 targets MECP2 and promotes microglial activation Poster Session IV 12
Michelle M. Jacobs HIV-related neurocognitive impairment is related to polymorphisms in CCR2 and CD163 in the absence of cocaine and opiate dependency Poster Session IV 13
Gregory Sartor BET bromodomains regulate neurobehavioral responses to psychostimulants Poster Session IV 14
Viranu Sueblingvong Alcohol induces profibrotic fibroblast phenotype via induction of DNA methyl transferase. Poster Session IV 15
Jasmin Vassileva Behavioral Phenotypes of Impulsivity in Substance Dependent Individuals in Protracted Abstinence: Insights from ‘Pure’ Heroin and Amphetamine Users Poster Session IV 16
Andrew Talal Telemedicine-based Management of Hepatitis C Virus (HCV) Infection for Individuals on Opiate Agonist Treatment Poster Session IV 17
Brion Maher A Novel Approach to Accounting for Exposure in Association Studies of Drug Use Disorders Poster Session IV 18
Rae Silver Novel noninvasive voluntary methamphetamine inhalation paradigm for long-term studies of neuroinflammation and drug-seeking behavior Poster Session IV 19
Kristin G. Ardlie Specificity of alternative splicing in brain tissues from the GTEx project Poster Session IV 20
Narasimhan J. Venkatachari Transcriptome analysis of Peripheral Blood Mononuclear Cells from individuals with HIV-1 associated neurocognitive disorder identifies key players associated with neuropathogenesis and Marijuana use. Poster Session IV 21
Pawel Cirborowski Systems biology approach reveals novel insights into altered functions of HIV-1-infected or methamphetamine exposed macrophages. Poster Session IV 22
Lee Campbell Creation and characterization of the HIV-nanoLuc CHME-5 cell line Poster Session IV 23
Bi Xuan A Statistical Method for Advancing Neuroimaging Genetics Poster Session IV 24
Tom Gould Paternal nicotine exposure trans-generationally alters fear response and cholinergic function: potential epigenetic mechanisms Poster Session IV 25
Dan Iancu Genetic Selection for Methamphetamine Intake Rewires Brain Transcriptional Networks Poster Session IV 26
Fereshteh S. Nugent Changes in neuronal excitability and histone modifications within the LHb may underlie anxiety and depression following early life stresses Poster Session IV 27
Shuanglin Hao Epigenetic modification of MCU in the spinal cord dorsal horn in chronic morphine tolerance and HIV-related neuropathic pain state Poster Session IV 28
Lucia Carvelli Embryonic exposure to amphetamine alters the activity of the dopamine transporter in adult animals and progeny Poster Session IV 29

This page was last updated December 2017