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Research suggests new genetic target to treat cocaine addiction

Science Spotlight

December 26, 2013

NIDA-funded research shows that a specific mutation in the CYFIP2 gene dramatically lowers responses to cocaine in a mouse model. The mutation appears to affect the CYFIP2 protein, a key player in processes underlying memory, learning, and habit formation.  This research provides a new target for research into potential medications to treat cocaine addiction.

Cocaine synapseCocaine synapse

For a copy of the study abstract, go to https://www.sciencemag.org/content/342/6165/1508.short.

For more information, contact the NIDA press office at media@nida.nih.gov or 301-443-6245.

Contact:
NIDA Press Office
301-443-6245
media@nida.nih.gov

About the National Institute on Drug Abuse (NIDA): The National Institute on Drug Abuse (NIDA) is a component of the National Institutes of Health, U.S. Department of Health and Human Services. NIDA supports most of the world’s research on the health aspects of drug use and addiction. The Institute carries out a large variety of programs to inform policy, improve practice, and advance addiction science. Fact sheets on the health effects of drugs and information on NIDA research and other activities can be found at www.drugabuse.gov, which is now compatible with your smartphone, iPad or tablet. To order publications in English or Spanish, call NIDA’s DrugPubs research dissemination center at 1-877-NIDA-NIH or 240-645-0228 (TDD) or email requests to drugpubs@nida.nih.gov. Online ordering is available at drugpubs.drugabuse.gov. NIDA’s media guide can be found at www.drugabuse.gov/publications/media-guide/dear-journalist, and its easy-to-read website can be found at www.easyread.drugabuse.gov. You can follow NIDA on Twitter and Facebook.

About the National Institutes of Health (NIH): NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit www.nih.gov.

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    NIDA. (2013, December 26). Research suggests new genetic target to treat cocaine addiction. Retrieved from https://www.drugabuse.gov/news-events/news-releases/2013/12/research-suggests-new-genetic-target-to-treat-cocaine-addiction

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