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Medication finds new use in sustaining opioid quit success

Science Spotlight

March 18, 2015

Image of a precription pad with a stethoscope over the top of it

New research suggests that clonidine, a medication for high blood pressure and attention deficit hyperactivity disorder (ADHD), can enhance buprenorphine’s ability to treat opioid dependence. This combination of medications reduces stress-induced craving and prolongs opioid abstinence during outpatient treatment for heroin or prescription pain reliever dependence, compared to buprenorphine alone.

These results show that clonidine, when combined with buprenorphine, could be another tool for clinicians who are treating patients in recovery from opioid misuse.

For a copy of the article, published in the American Journal of Psychiatry, and authored by scientists at NIDA, NIMH, and Spectrum Health System, go to: http://ajp.psychiatryonline.org/doi/full/10.1176/appi.ajp.2014.14081014.To learn more about research being conducted at NIDA in this area, go to: http://irp.drugabuse.gov/cptrb.php.

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About the National Institute on Drug Abuse (NIDA): The National Institute on Drug Abuse (NIDA) is a component of the National Institutes of Health, U.S. Department of Health and Human Services. NIDA supports most of the world’s research on the health aspects of drug use and addiction. The Institute carries out a large variety of programs to inform policy, improve practice, and advance addiction science. Fact sheets on the health effects of drugs and information on NIDA research and other activities can be found at www.drugabuse.gov, which is now compatible with your smartphone, iPad or tablet. To order publications in English or Spanish, call NIDA’s DrugPubs research dissemination center at 1-877-NIDA-NIH or 240-645-0228 (TDD) or email requests to drugpubs@nida.nih.gov. Online ordering is available at drugpubs.drugabuse.gov. NIDA’s media guide can be found at www.drugabuse.gov/publications/media-guide/dear-journalist, and its easy-to-read website can be found at www.easyread.drugabuse.gov. You can follow NIDA on Twitter and Facebook.

About the National Institutes of Health (NIH): NIH, the nation’s medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit www.nih.gov.

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    NIDA. (2015, March 18). Medication finds new use in sustaining opioid quit success. Retrieved from https://www.drugabuse.gov/news-events/news-releases/2015/03/medication-finds-new-use-in-sustaining-opioid-quit-success

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