NIDA Notes Articles: Relapse and Recovery

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Serotonin Receptor Agonist Lorcaserin Reduces Relapse to Drug Use in Monkeys

March 2020
The serotonin 2C receptor agonist lorcaserin reduced reinstatement of drug-seeking behavior in response to heroin or cocaine in a nonhuman primate model of relapse.

α2δ-1–NMDA Receptor Interactions Are Responsible for Increases in Pain Sensitivity Caused by Opioids

December 2019
In animal studies, α2δ-1 and its interactions with NMDA receptors in the spinal cord triggered the pain sensitivity and analgesic tolerance that occurs with chronic morphine treatment. Blocking the α2δ-1–NMDA interaction reduced opioid-induced hyperalgesia and analgesic tolerance.

Nerve-Cell Growth During Abstinence From Methamphetamine May Promote Reinstatement of Drug Use in Rats

November 2019
Neurogenesis that occurs during abstinence from methamphetamine in a brain region related to memory and learning may promote relapse-like behavior.

Methadone Maintenance Treatment During Incarceration Has Long-Term Benefits

April 2019
Prisoners who received methadone maintenance treatment (MMT) during incarceration were more likely than prisoners who did not receive MMT to engage in the treatment after being released.

Outcomes of Computerized CBT Rival Those of Clinician-Delivered CBT

June 2018
A clinical trial found that patients who self-administered cognitive behavioral therapy (CBT) using computerized training modules reduced their drug use as much as patients who received clinician-delivered CBT, and they maintained this advantage through a 6-month follow-up.

Cigarette Smoking Increases the Likelihood of Drug Use Relapse

May 2018
Research suggests that helping patients quit and remain abstinent from smoking may improve their chances for sustained recovery from use of other drugs.

Stressful Experiences Affect Likelihood of Remission of Drug Dependence, Continued Drug Use, and Relapse

February 2018
Stressful life events are associated with reductions in a person’s chances of becoming or remaining abstinent from drugs for at least 3 years.

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Serotonin Receptor Agonist Lorcaserin Reduces Relapse to Drug Use in Monkeys

α2δ-1–NMDA Receptor Interactions Are Responsible for Increases in Pain Sensitivity Caused by Opioids

Nerve-Cell Growth During Abstinence From Methamphetamine May Promote Reinstatement of Drug Use in Rats

Methadone Maintenance Treatment During Incarceration Has Long-Term Benefits

Outcomes of Computerized CBT Rival Those of Clinician-Delivered CBT

Cigarette Smoking Increases the Likelihood of Drug Use Relapse

Stressful Experiences Affect Likelihood of Remission of Drug Dependence, Continued Drug Use, and Relapse

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COVID-19 is an emerging, rapidly evolving situation.

NIDA Notes Articles: Relapse and Recovery

Serotonin Receptor Agonist Lorcaserin Reduces Relapse to Drug Use in Monkeys

α2δ-1–NMDA Receptor Interactions Are Responsible for Increases in Pain Sensitivity Caused by Opioids

Nerve-Cell Growth During Abstinence From Methamphetamine May Promote Reinstatement of Drug Use in Rats

Methadone Maintenance Treatment During Incarceration Has Long-Term Benefits

Outcomes of Computerized CBT Rival Those of Clinician-Delivered CBT

Cigarette Smoking Increases the Likelihood of Drug Use Relapse

Stressful Experiences Affect Likelihood of Remission of Drug Dependence, Continued Drug Use, and Relapse

Categories

Tags

Drug Topics

Drugs of Abuse

Population Groups

Related Topics